Track: Neurogenetics and Neurodegenerative Disease

Neurogenetics and Neurodegenerative Disease

Session Overview:

This session will comprehensively explore the critical intersection of genetics and neurodegenerative diseases, focusing on recent advancements in understanding and managing conditions like Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). Participants will delve into the intricate genetic mechanisms that contribute to the onset and progression of these debilitating disorders. The session will highlight groundbreaking research, including the identification of novel genetic markers and mutations, and examine how these findings are transforming our approach to diagnosis and treatment. Attendees will also learn about emerging therapeutic strategies, including gene-based therapies and personalized medicine approaches, aimed at targeting the root causes of these diseases. Through interactive discussions and expert presentations, this session aims to provide a comprehensive overview of current research and future directions in neurogenetics, offering valuable insights for clinicians, researchers, and healthcare professionals involved in neurodegenerative disease management.

Recent Developments:

Recent updates in neurogenetics and neurodegenerative diseases include significant genetic discoveries, such as new mutations linked to conditions like Alzheimer's and Parkinson's, which have advanced our understanding of hereditary factors and disease mechanisms. Innovations such as CRISPR-Cas9 gene editing and next-generation sequencing (NGS) are revolutionizing the field, allowing for precise genetic interventions and detailed genetic profiling. New clinical cases from ongoing trials are demonstrating promising results for gene-based therapies and personalized medicine, with advancements in Antisense Oligonucleotides (ASOs) showing potential for treating ALS. AI and machine learning are increasingly involved, offering predictive modeling to assess disease risk and progression, and accelerating drug discovery by analyzing genetic data to identify new therapeutic targets. Additionally, emerging treatments include gene therapies aimed at correcting genetic defects and immunotherapies designed to target toxic proteins, marking significant strides toward more effective diagnostics and treatments.

Sub-Tracks:

Genetic Basis of Neurodegenerative Diseases

Explore the genetic mutations and variations that contribute to diseases like Alzheimer's and Parkinson's, highlighting recent discoveries and their implications for disease mechanisms.

Advancements in Genomic Technologies

Review cutting-edge technologies such as CRISPR and next-generation sequencing, focusing on their applications in identifying genetic markers and understanding disease pathology.

Personalized Medicine and Targeted Therapies

Discuss how genetic insights are driving personalized treatment approaches and the development of targeted therapies, including current clinical trials and emerging treatments.

Role of Epigenetics in Neurodegeneration

Investigate how epigenetic modifications influence neurodegenerative diseases, including their impact on gene expression and potential therapeutic targets.

Integration of Genomics and Bioinformatics

Examine how bioinformatics tools and genomic data analysis are enhancing research into neurodegenerative diseases, leading to new discoveries and clinical applications.

Neurogenetic Biomarkers and Diagnostics

Exploration of genetic markers for early diagnosis and disease progression, including innovative diagnostic tools and techniques.

Genetic Modifiers of Neurodegenerative Disease

Investigation into how various genetic factors influence the onset, progression, and variability of neurodegenerative diseases.

Gene Therapy and Genetic Engineering

Developments in gene-editing technologies like CRISPR/Cas9 for therapeutic interventions and their potential applications in treating neurodegenerative disorders.

Neurogenetic Mechanisms of Aging

Study of how genetic factors contribute to age-related neurodegenerative changes and diseases.

Ethical and Social Implications of Neurogenetic Research

Examination of the ethical considerations and societal impact of genetic research and interventions in neurodegenerative diseases.