Virtual Conference

Pholpipat Bunluesin

Phramongkutklao Hospital, Thailand

Title: The impact of covid-19 on physical and mental health of patients with drug-resistant focal Epilepsy


Objective: During the third wave of COVID-19 in Thailand, researchers aimed to see how people with drug resistant focal epilepsy (DRE) experienced about anxiety, depression, seizure frequency, and quality of life.

Method: At visit-1 (baseline) and visit-2 (1-month follow-up), we asked patients with DRE who visited our Neurology Clinic Phramongkutklao Hospital to complete questionnaires to assess anxiety (Hamilton Anxiety Rating Scale; HAM-A), depression (Patient Health Questionaire-9 Thai version; PHQ-9T), and quality of life (Patient Weighted Quality Of Life in Epilepsy-10; QOLIE-10). In addition, a seizure diary was collected in order to determine seizure frequency.

Result: From July to September 2021, ten individuals with DRE (six males, average age 36.8 years) took part in the study and performed evaluations twice, one month apart. The median monthly seizure frequency was decreased from 3 to 1 after a one-month survey, p=0.072. The HAM-A average and range were increased slightly from 12.0to 13.6, with a p-value of 0.135. PHQ-9 averages were 6.40 and 6.80, respectively, with a p-value of 0.791. The QOLIE-10T score was lowered from 39.8 to 38.7, with a p-value of 0.800.

Conclusion: The third wave of COVID-19 in Thailand had no effect on the physical or emotional wellbeing of individuals with drug-resistant focal epilepsy.


Division of Neurology, Department of Medicine, Phramongkutklao Hospital, Thailand